Relationship Between Scapular Muscle Performance And Grip Strength In Lateral Epicondylitis Among Computer Operators

Background: Lateral epicondylitis is an overuse injury of the tendon and involving the extensor muscle of forearm. Induced pain at the upper trapezius (UT) produces an increase in wrist extensor electromyographic activity (EMG) which could potentially lead to overuse injury, such as LE, at the elbow. Some studies found that there is a relation between scapular muscle muscle performance and lateral epicondylitis and loss of grip strength in lateral epicondylitis. There is a lack of literature of similar studies among computer operators. The most common wrong working posture in computer operator is excessive wrist extension it causes to the overuse injury like lateral epicondylitis. The context and purpose of the study: To find out the relationship between scapular muscle performance and grip strength in lateral epicondylitis among computer operators. Result: The correlation between scapular muscle performance and grip strength in LE among computer operators was done using Karl Person correlation coefficient. The result indicated that there is a significant relation between scapular muscle performance and grip strength in lateral epicondylitis. Conclusion: The study showed that there is an impairment of scapular muscle performance and grip strength in lateral epcondylitis among computer operators. Implication: Regular physical activity and proper ergonomics advice can improve quality of life among computer operators.

Comparison Of Neck Muscle Flexibility, Strength, Endurance And Proprioception Among The Video Display Terminal User’s In College Students With Neck Pain And Without Neck Pain

Background: Neck pain is one of the main causes of those who use video display terminal devices. Prolonged period of work in an awkward posture would mainly lead to neck pain among the VDT users. Studies show the prevalence of neck pain among VDT users as 45.5%. It is essential to identify factors for preventing people from getting neck pain. Studies show that musculoskeletal disorders are related to physical fitness level. Many factors in physical fitness can predict the incident of musculoskeletal disorders. There are still studies which are specific to neck pain and physical fitness in office workers. The context and purpose of the study: The main aim of the study is to compare the flexibility, strength, endurance and proprioception of neck among the VDT users in college students with neck pain and without neck pain. Results: The main finding of this study was that the video display terminal device users who use more than 4 hours / day have significantly lower flexibility, endurance and proprioception among student with neck pain compared to without pain VDT devices students. But there is no significant difference in strength among both groups. Conclusion: The majority of VDT user’s students who have neck pain are more affected in range of motion, endurance and proprioception compare to without neck pain. But there is no significant difference in strength among both groups. Implication: static posture without taking break in student who use VDT devices can be decrease in physical fitness of neck, so student are take break in between time to time and stretch their leg as well as arm ,neck.

Primary Intestinal Lymphoma: A Clinicopathological Study.

Introduction: Primary intestinal lymphoma (PIL) is defined as an extranodal lymphoma arising in the intestine. This study includes 11 PILs. Objectives: The objective of this study was to evaluate the clinicopathological characteristics of primary non-Hodgkin's lymphoma (NHL) in the small and large intestine. All cases were reclassified according to the World Health Organization classification of lymphoma in 2001. Immunohistochemistry (IHC) was used to confirm the histopathological diagnosis. Materials and Methods: Eleven cases of primary non-Hodgkin in the small and large intestine were studied retrospectively in a 5 year period. There were seven cases of resected intestinal specimens and four biopsy specimens. Five cases from ileum and two cases each from caecum and duodenum and one case each from jejunum and duodenum. Hematoxylin and eosin stained sections were studied with light microscopy and IHC for CD5, 20, 21 and cyclin D1 were done. Results: It is a retrospective study of 11 cases of intestinal lymphomas. Abdominal pain and abdominal lump were two main common presenting symptoms. NHLs were more common in the small intestine. PILs are common in adults (75% above 46 years) with male preponderance. All were NHLs and B-cell type. Five cases were diffuse large B-cell lymphoma and four cases each were mucosa-associated lymphatic tissue lymphoma and follicular lymphoma. One case was lymphomatoid polyposis or mantle cell lymphoma. Conclusion: PILs is rare and differs significantly from their gastric counterpart, not only in pathology but also with regard to clinical features, management and prognosis. Due to the lack of characteristic symptoms and a low incidence rate, PIL is misdiagnosed until serious complications occur, such as perforation and bleeding and hence needs to be accurately diagnosed.

Serum and salivary sialic acid as a biomarker in oral potentially malignant disorders and oral cancer.

Background: Aberrant glycosylation is the universal feature of cancer and components of various glycoconjugates, such as sialic acid is found to rise in various malignancies. The objective of this study was to evaluate the serum and salivary sialic acid in oral potentially malignant disorders (OPMD) and oral cancer (OC) to investigate the possibility of using this as a diagnostic marker. Materials and Methods: The study included 85 subjects, who were grouped as control (30), OPMD patients (25), and oral cancer patients (30). Serum and unstimulated whole saliva was collected from subjects of all groups and sialic acid estimation was done using spectrophotometry. The results were tabulated and analyzed statistically. Results: The mean serum sialic acid levels in normal, OPMD, and oral cancer group were 7.515, 19.620, and 55.235 mg/dL, respectively, whereas the levels of salivary sialic acid were 1.5113, 2.3302, and 9.0304 mg/dL, respectively. A very highly significant rise (P < 0.005) in serum and salivary sialic acid was observed in the study subjects compared with that of the control. Conclusions: The present study showed a significant and gradual increase in serum and salivary sialic acid from control to oral potentially malignant disorders to oral cancer. From this study we can suggest that sialic acid can be used as a reliable biomarker. As this monosaccharide is observed in saliva in detectable quantity, saliva can be used as a diagnostic medium for screening and early detection of oral cancer.

Death due to isolated mesenteric vascular injury following blunt abdominal trauma: A case report.

Death due to isolated injury to small bowel mesentery following abdominal trauma is rare. It is known that seatbelt trauma from motor vehicle accidents is the most common mechanism of mesenteric injury and that the mesentery of the small bowel is injured more frequently than that of the colon. Focal mesenteric infiltration associated with haemoperitoneum, particularly in the absence of solid organ injury, is highly suggestive of a mesenteric tear. In this report one such seat belt abdominal injury with subsequent mesenteric tear and bowel infarction with significant haemoperitoneum leading to death on the Operation table is being discussed. The main significance of this injury is delay and difficulty in diagnosis, especially when there is minimal signs and symptoms to warrant an exploratory laparotomy. Early detection and emergency surgical intervention when necessary are critical in improving the outcome of treatment.

Pattern of homicidal deaths.

Killing of an individual is the highest level of aggression found in all cultures. Incidence of Homicide is on the rise worldwide and pattern is also changing except for the motive v.i.z. lust for money, women and land. The present prospective study from Oct 2005 to Sep 2007 for a period of 2 years in the Dept of Forensic Medicine, MS Ramaiah Medical College, Bangalore revealed that homicidal deaths accounted for 4.32% of autopsies and victims in the age group 20-29 years constituted 49.25% of cases. In 12.25 % of cases Police did not suspect homicide prior to autopsy. Maximum homicides took place at victim‘s residence (31.5%) and street (29.75%). Acquaintances were involved in 47% of cases. The main motive was revenge (26.5%). Sharp weapon injuries (33.25%) were the commonest pattern followed by blunt weapon injuries (28%) and 82.5 % of victims died on the spot.

Floating thromboembolism: a case report.

Medico legal autopsies are conducted in cases of sudden unexpected deaths, primarily to establish the cause of death. In cases where deaths have occurred in apparently healthy individuals, deaths under suspicious circumstances or who have sustained injuries, pulmonary embolism forms the principal cause of sudden unexpected death. Pulmonary thromboembolism (PTE) is caused when thrombi are detached from the deep vein of the lower leg. The most important causes for incorrect diagnosis are failure to suspect Pulmonary Embolism, and the protean nature of the disease. Presentation is often “atypical”. Signs and symptoms are frequently vague and nonspecific and rarely “classic”. In more than 95% of cases, venous emboli originate from deep leg vein thrombi above the level of the knee. Most pulmonary emboli (60 to 80%) are clinically silent because they are small. Remarkable differences actually exist concerning the point of origin and the final localization, as well as the size and age of thromboemboli, the presence or absence of pulmonary infarction, and the underlying pathology. This paper highlights a rare case of a young individual with minor injuries who succumbed to pulmonary thromboembolism.

Nodular regenerative hyperplasia of liver.

Nodular regenerative hyperplasia of the liver (NRHL) is a very rare cause of portal hypertension and liver failure. The condition is characterized by diffuse micronodular transformation of hepatic parenchyma without fibrous septa between the nodules. We present our experience with a 32-year-old woman who presented with recurrent episodes of upper gastrointestinal bleeding associated with massive splenomegaly who was subsequently found to have NRHL. This article considers the salient aspects of this rare condition, how it affects the patients and the options available in its management. A plea is made for the need for liver biopsy for all patients with portal hypertension especially those being considered for surgery.

Antioxidant modulation in response to heavy metal induced oxidative stress in Cladophora glomerata.

The present investigation was carried out to study the induction of oxidative stress subjected to heavy metal environment. Lipoperoxides showed positive correlation at heavy metal accumulation sites indicating the tissue damage resulting from the reactive oxygen species and resulted in unbalance to cellular redox status. The high activities of ascorbate peroxidase and superoxide dismutase probably counter balance this oxidative stress. Glutathione and soluble phenols decreased, whereas dehydroascorbate content increased in the algae from polluted sites. The results suggested that alga responded to heavy metals effectively by antioxidant compounds and scavenging enzymes.

Adaptive response to low dose of EMS or MMS in human peripheral blood lymphocytes.

Human peripheral blood lymphocytes stimulated in vitro for 6 hr were exposed to a low (conditioning) dose of ethyl methanesulfonate (EMS; 1.5 x 10(-4) M) or methyl methanesulfonate (MMS; 1.5 x 10(-5) M). After 6 hr, the cells were treated with a high (challenging) concentration of the same agent (1.5 x 10(-3) M EMS or 1.5 x 10(-4) M MMS). The cells that received both conditioning and challenging doses became less sensitive to the induction of sister chromatid exchanges (SCEs) than those which did not receive the pretreatment with EMS or MMS. They responded with lower frequencies of SCEs. This suggests that conditioning dose of EMS or MMS has offered the lymphocytes to have decreased SCEs. This led to the realization that pre-exposure of lymphocytes to low dose can cause the induction of repair activity. This is a clear indication of the existence of adaptive response induced by alkylating agents whether it is ethylating or methylating in human lymphocytes in vitro.

Inducible protective processes in animal systems: adaptive response to a low dose of methyl methanesulfonate in mouse bone marrow cells.

To investigate the induction of adaptive response (inducible protective processes) in mitotic cells of Swiss albino mouse, a monofunctional alkylating agent methyl methanesulfonate (MMS) was employed. When the animals treated with a low dose of 50 mg/kg body weight were challenged with a subsequent high (challenging) dose of 150 mg/kg body weight, after different time lags (2,5,8 or 10 hr), the yield of chromosomal aberrations in bone marrow cells was found to be significantly reduced compared to the additive effects of both conditioning and challenging doses. It seems, therefore, that the low dose of MMS employed has made the cells less sensitive against further clastogenic effect of challenge dose of MMS. The data clearly suggest that the phenomenon of adaptive response to methylating agents can be encountered in in vivo mammalian cells. Furthermore, it is also observed that ethylating agent EMS is a poor inducer of adaptive response than its corresponding methylating agent MMS in the bone marrow cells of mouse.